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diagnosis smear blood causes cell dic disseminated electrophoresis gammopathy igm indications intravascular leukemia management mgus microscopy plasmacell plasmacytoma protein serum
Rouleaux formation is common in IgM gammopathy and may be particularly striking Genevieve Crane, MD, PhD@evemariecrane #Rouleaux #formation
Rouleaux formation ... evemariecrane #Rouleaux ... #formation #IgM ... gammopathy #MGUS #Clinical ... #Pathology #Hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
with extensive rouleaux ... formation. ... #formation #Clinical ... #Smear #Hematology ... #Pathology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
formation” wherein ... normal blood tends ... dilution with normal ... #Clinical #Pathology ... #Formation #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... significant fibrin clot formation ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal ... treatment #management #hematology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
fatigue, bone pain, abnormal ... bleeding) • Rouleaux ... formations noted ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... mainly in the oral ... IFE, FLC assay Pathology ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
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