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diagnosis hematology mds myelodysplastic anemia apml chronic classification differentiation druginduced gout hodgkins leukemia lupus lymphocytic lymphoma myelodysplasia sjogrens sle syndromes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... ) -plastic (shape ... Allogeneic stem cell ... #treatment #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
(MDS) (normal or ... megakaryocytes and a normal ... anemia Treatment ... #Anemia #oncology ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... aplasia • ITP ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... Myeloproliferative Disease ... blood cells appear normal ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Induce blast cell ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... CRP - Usually normal ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
phenomenon (16%) MSK ... Adenocarcinoma Treatment ... Pharmacologic: • Severe oral ... #Rheumatology # ... Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... products that define normal ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #oncology #management
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... forefoot, ankles, knees ... Dual-energy CT → MSU ... #treatment #rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
, Lyme disease, ... phosphatase - Normal ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management ... #rheumatology #
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