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diagnosis algorithm oncology causes classification disorders management approach globulin hodgkins lymphoma markers mds myelodysplasia myelodysplastic platelet protein proteingap syndromes thrombocytopenia
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Workup #Differential ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Workup #Differential ... Diagnosis #Algorithm #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... bone marrow + pancytopenia ... result from low blood ... #hematology #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm Blood ... RBC Production - Normal ... Deficiency • Aplastic ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... plateletcount), peripheral blood ... changes), high MCV anemia ... ITP, unexplained pancytopenia ... #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - Markers and Differential ... Pelger-Huet, Macrocytic anemia ... Amy Chung, MD, MSc ... #Disorders #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... Workup: • Complete ... differential • ... Syndromes #diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
levels - Usually normal ... of Peripheral blood ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gastric tumors • Hematology ... light chain • Normal ... #ProteinGap #differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
products that define normal ... Hodgkin Lymphoma Workup ... : • Full Blood ... Immunohistochemical studies (to differentiate ... classification #hematology
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