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diagnosis management hematology signs neurology oncology algorithm apml caudaequina classification differential differentiation disorders erythematosus fungal infections infectiousdiseases injury leukemia lupus
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... / Complications ... Areflexia (loss of normal ... reflexes) • Urinary ... #MSK #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... 500 mg QD until normal ... Differentiation #Syndrome
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... + distinctive primary ... • Tumor lysis syndrome ... Transformation: • Complication ... #Leukemia #Hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... and progressive Acute ... anterior/posterior MSK ... ), liver (pain/abnormal ... : ACUTE, fever,
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
can have extra nodal ... pattern of spread, B symptoms ... Treated Like Acute ... Amy Chung, MD, MSc ... Classification #pathophysiology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... • Primary Progressive ... ) • Acute: ... daily 3-5 days - Oral ... mg) without an oral
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... Classification: • Acute ... the context of primary ... Pleural effusions • Acute ... Induced Lupus: • Symptoms
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
presents with acute ... • Rheumatologic ... gastrointestinal 4) Primary ... level • A low or normal ... Aspergillosis Pathophysiology
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