9 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
(SLE): Musculoskeletal ... Myopathy (Also caused ... #MSK #Musculoskeletal ... Complications #pathophysiology ... #signs #symptoms
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #CNS #neurology ... cerebritis #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... (MDS) (normal or ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... are not caused ... skin (16-32%): lupus ... anterior/posterior MSK
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... Psychiatric symptoms ... Loss of teeth Anemia ... nonimmune hemolysis MSK ... , or any other cause
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... and pernicious anemia ... Pathophysiology ... Oligoclonal bands • Normal ... #treatment #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... • Infectious causes ... Myelitis #diagnosis #management ... #neurology #differential
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... the underlying pathophysiology ... #diagnosis #management ... #neurology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... and the systemic symptoms ... phosphatase - Normal ... TAFRO #diagnosis #management