19 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... #Nephritis #SLE ... Classification #Classes #differential ... #diagnosis #management ... #nephrology
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
of Membranous Lupus ... proteinuria (<3.5g/d, normal ... treat non-renal SLE ... #Treatment #management ... #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... sedimentation rate + Normal ... permanent alopecia Differential ... : • Symptoms limited ... flares • CRP normal
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... CRP - Usually normal ... constitutional symptoms ... ulcers, Lupus nephritis ... - CRP: Usually normal
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... #CNS #neurology ... cerebritis #diagnosis #management
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Ischemic optic neuritis ... - SLE Neurologic ... arthritis ENT • Oral ... syndrome, Reactive ... #joint #pain #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Behcet disease) Differential ... aphthae : SLE, ... #diagnosis #management ... #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Guillain-Barré syndrome ... GBS), systemic lupus ... erythematosus (SLE ... Stop statin • Oral ... myopathy #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... skin (16-32%): lupus ... ), liver (pain/abnormal ... Sarcoidosis #Diagnosis #Management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... objective evidence of neurologic ... mg) without an oral ... sclerosis #diagnosis #management ... #neurology #treatment