31 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... : • Pathophysiology ... diagnosis #management #hematology
Adie's Pupil
What? Unknown nature & benign
 • Regular and mildly dilated pupil (4-6mm);
 • Light-near dissociaton;
reexposed to light; • Normal ... Holmes-Adie Syndrome ... Ill Palsy - abnormal ... #Adies #Pupil #PhysicalExam ... #neurology #ophthalmology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... spine Signs / Symptoms ... Areflexia (loss of normal ... #MSK #pathophysiology ... #diagnosis #symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... 500 mg QD until normal ... Differentiation #Syndrome
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
should reveal normal ... acuity If any are abnormal ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... meningitis), MCC CNS symptoms ... tests in Behcet syndrome ... inhibitors • Uveitis- Ophthalmology ... management #signs #symptoms
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Risk of Refeeding Syndrome ... from any source; oral ... #diagnosis #pathophysiology ... #symptoms #signs
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Conjugation == Gilbert Syndrome ... hyperbilirubinemia syndrome ... of about 30% of normal ... examination; nonspecific symptoms ... Congenital #bilirubin #hepatology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Xerophthalmia - abnormal ... #Xeropthalmia #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... (MDS) (normal or ... megakaryocytes and a normal ... • Improve the symptoms ... Anemia #oncology #hematology