64 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... CSF PROTEIN - NORMAL ... Treatment: • Plasmapheresis ... #management #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... protein with a normal ... than one after symptom ... the underlying pathophysiology ... and cauda equina TREATMENT
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... hyperkalemia) BRASH Treatment ... • Aggressive treatment ... balanced fluids" > normal ... diagnosis #management #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... organ damage • Treatment ... : • Pathophysiology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... myopathy, Guillain-Barré ... syndrome (GBS), ... antisynthetase syndrome ... Stop statin • Oral
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... spine Signs / Symptoms ... Areflexia (loss of normal ... #MSK #pathophysiology ... #diagnosis #symptoms
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
(MDS) (normal or ... CMV) • Epstein-Barr ... megakaryocytes and a normal ... aplastic anemia Treatment ... • Improve the symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... meningitis), MCC CNS symptoms ... Arthritis, AS Treatment ... inhibitors • Uveitis- Ophthalmology ... management #signs #symptoms
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Eosinophilia and Systemic Symptoms ... (DRESS) Syndrome ... Treatment Stop ... topical steroid +/- oral ... #Treatment #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Diagnosis: >3 symptoms ... 500 mg QD until normal