13 results
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Sheet: Warfarin, Apixaban ... - Resume #Oral ... #Anticoagulation ... Management #Table #Pharmacology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Bridging #Dosing #Oral ... Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
of Clearance of Oral ... Hepatic, 0% Renal Apixaban ... NOAC #Metabolism #Pharmacology ... #Clearance #oral ... #anticoagulation
Xa Inhibitors - Apixaban and Rivaroxaban 
Oral Xa inhibitors are recommended by CHEST as first-line for
Xa Inhibitors - Apixaban ... Rivaroxaban Oral ... Fibrillation requiring anticoagulation ... patients with normal ... Rivaroxaban #Dosing #Pharmacology
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
- Rivaroxaban; apixaban ... • Once a day oral ... Gl bleed - VKA, apixaban ... decisionaid #vte #anticoagulation ... #pharmacology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Fondaparinux, and Novel Oral ... subcutaneous) and oral ... fondaparinux) or a new oral ... a traditional oral ... Rivaroxaban: A new oral
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Diabetes Combination ... /ambcarerx #Diabetes ... Combination #Tablets #Oral ... #DM2 #Pharmacology ... #Pills #Endocrinology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic algorithm ... Supplementation (oral ... • Drugs • Diabetic ... Nephropathy Renin Normal ... #nephrology #potassium
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... direct acting oral ... may not require anticoagulation ... inhibitor) • Apixaban ... Management #Treatment #pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Most effective oral ... #Metformin #Pharmacology ... #Summary #DM2 #diabetes ... #endocrinology