21 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution ... context of other symptoms ... SLE), Sjogren's Syndrome ... #rheumatology #diagnosis ... #differential
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytes • Median ... lymphadenopathy and ... 3) Monoclonal antibodies ... Lymphocytic #Leukemia #oncology ... #diagnosis #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... Cold Agglutinin Syndrome ... younger pts) Differential ... hemolytic #anemia #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Medium and large ... Behcet disease) Differential ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
Pain (Otalgia) - Differential ... 10%) • Otitis media ... symptoms: headache ... • Associated symptoms ... Otalgia #Ear #Pain #Otology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... MEDIUM VESSEL ... Presentation - Systemic Symptoms ... ) pattern: antibodies ... #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Auto-antibodies ... or serologies + symptoms ... blood retum in serial ... #differential # ... diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies