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Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Differential Diagnosis ... Management Summary Causes ... Dermatomyositis Clinical Features ... Hyperuricemia • Hyponatremia ... injured muscles - HYPOTENSION
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Workup and Differential ... Diagnosis Approach ... with previously stable ... Neurologic disorders ... #Workup #causes
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
Hypertension - ... Differential Diagnosis ... (correction of hypokalemia ... free cortisol excretion ... #Workup #table
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Differential Diagnosis ... injured muscles -> HYPOTENSION ... per day until stable ... Dialysis for severe hyperkalemia ... Management #Summary #causes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Tumor lysis syndrome ... - Rhabdomyolysis ... Excretion: • ... #causes #potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Tumor lysis syndrome ... - Rhabdomyolysis ... Excretion: • ... #causes #potassium ... #high #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Excretion Carbonic ... • Diagnosis of ... Loop Diuretics; High-Ceiling ... Kidney stones caused ... #Medications #Table
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
diuresis can be high ... Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #differential #diagnosis ... #table #sodium
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... K+ Excretion: ... reabsorption) Workup ... excretion ... Elimination (see Table