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diagnosis liver algorithm lfts obstetrics ascites biliary chemistry cholangitis comparison disease fatty hellp hepatorenal hrs hypertension injury interpretation liverenzymes management
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Wilson's • Pregnancy ... - AFLP, HELLP ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
(ICP) • Onset ... and hemorrhage Acute ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... #hepatology #obstetrics
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... /acute hepatitis ... Fatty liver of pregnancy ... #Diagnosis #causes ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... melanoma, myeloma • Pregnancy ... : < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... • Near normal ... : < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... cholestasis of pregnancy ... diagnosis #workup #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
disease - Cirrhosis ... - Alcoholic hepatitis ... fibrosis - Acute ... fatty liver of pregnancy ... #hepatology #SAAG
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
liver disease: cirrhosis ... severe alcoholic hepatitis ... , or acute liver ... Normal kidney ultrasound ... Hepatorenal #Syndrome #Hepatology
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