8 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
- TTP/HUS, HELLP ... (AFLP) Three syndromes ... child * Severe cases ... #AFLP #obstetrics ... #hematology #diagnosis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
coagulation defects. 1) HELLP ... child * Severe cases ... #TTPHUS #HELLP ... #AFLP #Obstetrics ... #OBGyn #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Antithrombin Ill • Ultrasound ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Preeclampsia, HELLP ... #hepatology #obstetrics
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Wilson's • Pregnancy ... - AFLP, HELLP ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential # ... #AFLP
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... biliary obstruction, HELLP ... Toxic: Medication, Pregnancy ... Acute #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Algorithm Vascular Causes ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... cholestasis of pregnancy ... diagnosis #workup #hepatology