14 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... of Pregnancy (AFLP ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... diagnosis #table #comparison
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... of Pregnancy (AFLP ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... #Elevation #Differential ... Diagnosis #Algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Pregnancy #hepatology ... #obstetrics #obgyn
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Hemolysis, Elevated Liver ... TTPHUS #HELLP #AFLP ... #Obstetrics #OBGyn ... #Hematology #Diagnosis ... #Comparison #Table
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... • Near normal ... disease: > 2 ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Pregnancy - AFLP ... • Cholestatic disease ... Others #LFTs #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Venoocclusive disease ... disease: > 2 ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
) • Advanced Liver ... Disease - Alcohol ... Septic shock, Obstetric ... Summary #table #comparison ... #diagnosis #hematology
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... , Metastasis #Liver ... POCUS #radiology #differential ... #diagnosis #comparison ... table #appearance #hepatology