13 results
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... Hepatocellular Pattern #LFTs ... pregnancy #obgyn #obstetrics ... #hepatology #diagnosis ... #differential #
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... #Diagnosis #hepatology ... Transaminitis #LFTs
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... or symptoms of liver ... disease 6-9 mo ... Idiosyncratic #differential ... gastroenterology #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
) • Advanced Liver ... Disease - Alcohol ... Septic shock, Obstetric ... Summary #table #comparison ... #diagnosis #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... #Disease #Pregnancy ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... disease: > 2 ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... , Metastasis #Liver ... POCUS #radiology #differential ... #diagnosis #comparison ... table #appearance #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... #Pregnancy #hepatology ... #obstetrics #obgyn
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... the spleen or liver ... involvement Differential ... #NonHodgkins #comparison ... #hematology