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management signs hematology algorithm behcet cancer chronic cll differential disease erythematosus immune inflammatory leukemia lupus lymphocytic manifestations neurology neuromyelitis nmo
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... noncompliance • Clinical ... initiation Clinical ... weeks for most OI ... #Inflammatory #Syndrome
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... pain/pain upon eye ... pain • Extra-CNS complications ... Manifestations #diagnosis ... #neurology #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Weight loss (50%) Eye ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... : Inflammatory eye ... (Clinical Dx). ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... vessels (aorta) • Eyes ... Multiple myeloma Complications ... Polychondritis #rheumatology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... Myelodysplastic syndromes ... of death from complications ... median age at diagnosis ... importance of clinical
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