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leukemia chronic lymphocytic mds syndrome aplastic apml classification differentiation gammopathy hemeonc hodgkins lymphoma mgus monoclonal myelodysplasia significance syndromes treatment undetermined
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... = funny-shaped cells ... cytopenias (usually anemia ... Allogeneic stem cell ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... count (anemia) ... • Aplastic Anemia ... #Syndromes #diagnosis ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... - infiltrates (anemia ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Diagnosis: • ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... lymphocytes, smudge cells ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Hypocellular myelodysplastic ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... constitutional symptoms ... insufficiency, Anemia ... to the plasma cell ... #diagnosis #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... ingestion • B symptoms ... classification #hematology ... #oncology #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Release from blast cells ... • Induce blast cell ... : >3 symptoms, or ... #management #hematology ... #oncology
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