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diagnosis hematology syndrome rheumatology anterior causes cll differentiation disease immune inflammatory lymphocytic mds myelodysplasia myelodysplastic ophthalmology reconstitution signs uveitis vasculitis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome ... #Hematology #Oncology
Causes of Anterior Uveitis - Differential Diagnosis Anterior Uveitis - 90% of cases of Uveitis • Inflammation
middle layer of the eye ... • Anterior-iris ... Immunocompromised-CMV • Chronic ... Inflammatory: Behcet's ... : Malignancy - Leukemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... • Sezary syndrome ... #CLL #Chronic ... diagnosis #workup #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
: Inflammatory eye ... disease) Differential ... tears, Ischemia, Leukemia ... Recurrent and chronic ... #management #signs
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... initiation • Differential ... #management #hematology ... #oncology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... weeks for most OI ... #Inflammatory #Syndrome ... #Differential # ... Diagnosis #Management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... Myelogenous Leukemia ... blood count with differential ... diagnosis #hematology #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... • Progressive symptoms ... Eosinophilia, asthma, chronic ... vasculitis • Behcet
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