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hematology differential leukemia hemeonc lymphocytic syndrome cns differentiation emergencies immune infectiousdiseases inflammatory mds myelodysplasia myelodysplastic neurology oncologic opportunistic reconstitution rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... ALL Symptoms: ... ) CLL Symptoms: ... Leukemia #Hematology #Oncology ... #Diagnosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Diagnosis Framework ... • IRIS might ... patients with IRIS ... #AIDS #opportunistic
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
/AIDS patients ... be present: • AIDS ... increase in CD4+ cells ... weeks for most OI ... #Management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... weeks without infection ... Diagnosis: • ... #workup #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... : >3 symptoms, or ... : Infection (sepsis ... #diagnosis #management ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... Complications: 1) Infection ... #Leukemia #oncology ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... • Parvovirus infection ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
if SSTI or port infection ... abdominal pain; full infectious ... “big & sticky” cells ... ± tocilizumab; call ... #HemeOnc #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... CRP GCA (Giant Cell ... • Progressive symptoms ... Eosinophilia, asthma, chronic
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