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hematology syndrome chronic cll lymphocytic mds anemia aplastic differential differentiation hemeonc immune inflammatory myelodysplasia reconstitution syndromes treatment workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... Malaise, bleeding, infections ... smear: Blasts APML ... #Hematology #Oncology ... #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... = funny-shaped cells ... risk-stratification • Risks: infection ... transformation to acute leukemia ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... • Hairy Cell Leukemia ... • Parvovirus infection ... #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... phenomenon CLL Diagnosis ... #diagnosis #workup ... #oncology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Release from blast cells ... : >3 symptoms, or ... : Infection (sepsis ... #diagnosis #management ... #hematology #oncology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
increase in CD4+ cells ... leukoencephalopathy (PML ... with severe symptoms ... weeks for most OI ... #Management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphocytes, smudge cells ... Complications: 1) Infection ... #oncology #hematology ... #hemeonc #diagnosis ... #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
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