9 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune ... with no early symptoms ... aplasia • ITP ... microglobulin Treatment ... diagnosis #workup #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... anemia Treatment ... • Improve the symptoms ... #Anemia #oncology ... hematology #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
increase in CD4+ cells ... pleural effusions, CNS ... weeks for most OI ... #IRIS #Immune ... Differential #Diagnosis #Management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
IRIS might ... less than 200 cells ... Antimicrobial treatment ... required until immune ... patients with IRIS
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... Renal Failure Treatment ... #diagnosis #management ... #hematology #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
“big & sticky” cells ... shortness of breath - Treatment ... → no immediate treatment ... ) - Treatment: ... ± tocilizumab; call
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Causes • Anemia • Aplastic ... Significance (IDUS) • Immune ... factor (GCSF) treatments ... diagnosis #hematology #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Erythema nodosum • Immune ... ingestion • B symptoms ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology ... #management
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
involved in immune ... • Pulmonary Symptoms ... CNS involvement: ... TREATMENT OPTIONS ... Histiocytosis #Diagnosis #Management