25 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... cells -> Mutagenic ... / Symptoms / Complications ... detachment • Red Eye ... Retinoblastoma #pathophysiology
Psoriatic Arthritis: Complications

 • Ocular - Inflammation of middle layer of the eye (the uvea, which
middle layer of the eye ... which includes the iris ... Cardiac - Valvular disease ... #diagnosis #signs ... #symptoms #Complications
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
• The disease ... gradient bows iris ... damage & blindness Signs ... / Symptoms / Complications ... ClosedAngle #Glaucoma #pathophysiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... should be done in ALL
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Contact lens use • Eye ... rubbing • Atopic diseases ... / Symptoms / Complications ... • Rizutti's Sign ... #Keratoconus #pathophysiology
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
disease progresses ... column) • Late complication ... AnkylosingSpondylitis #pathophysiology ... #diagnosis #signs ... #symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... increase in CD4+ cells ... such as double ... weeks for most OI ... Differential #Diagnosis #Management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Presentation: - Disease ... course of the disease ... fasciculations Common Symptoms ... neurology #diagnosis #management
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... history of the disease ... Signs of immunodeficiency ... /Symptoms/Findings ... Agammaglobulinemia #XLinked #pathophysiology