17 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
/ Symptoms: - ... Keratoconjunctivitis sicca (Dry eyes ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... Diagnosis - Based ... Signs and symptoms ... #diagnosis #management
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
inflammation (Scleritis ... interstitial lung disease ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms ... #diagnosis #ExtraArticular
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Pathophysiology ... Presentation: - Disease ... course of the disease ... fasciculations Common Symptoms ... #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
: Inflammatory eye ... meningitis), MCC CNS symptoms ... Genital ulcers • Eye ... #diagnosis #management ... #signs #symptoms
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... weeks for most OI ... #Inflammatory #Syndrome ... #Management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis of tumor cells ... #TLS #diagnosis ... #management #hematology
Psoriatic Arthritis: Complications

 • Ocular - Inflammation of middle layer of the eye (the uvea, which
middle layer of the eye ... which includes the iris ... Cardiac - Valvular disease ... #diagnosis #signs ... #symptoms #Complications
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Presentation - Systemic Symptoms ... Arthralgias • Eye ... , particularly scleritis ... purpura: strong sign ... Eye -> retinopathy
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... #Management #Signs