13 results
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... endothelial lining of blood ... nephrotic/nephritic syndrome ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Schonlein Purpura (IgA ... Presentation - Systemic Symptoms ... Arthralgias • Eye ... purpura: strong sign ... Eye -> retinopathy
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Arthralgias • Eye ... purpura: Strong sign ... pulses, bruits, or blood ... • Progressive symptoms ... Schonlein Purpura (IgA
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Nodules • Auto-immune ... vessels (vasculitis ... interstitial lung disease ... pathophysiology #signs ... #symptoms #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... ) • Blood smear ... sensitize red blood ... cells (RBCs) at
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
: Inflammatory eye ... meningitis), MCC CNS symptoms ... Genital ulcers • Eye ... #diagnosis #management ... #signs #symptoms
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine • 1ml blood ... Hematuria: • Immune ... hematuria • Signs ... of GN or vasculitis ... of glomerular disease
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... worsening of that disease ... weeks for most OI ... #Inflammatory #Syndrome ... #Management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Weight loss (50%) Eye ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Episcleritis Signs ... and Symptoms: ... Leukocytoclastic vasculitis ... neutrophils in the blood