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diagnosis differential gastroenterology irritable rheumatology treatment anemia aplastic chronic cll disease hemeonc hemophagocytic hlh immune inflammatory leukemia leukostasis lymphocytic lymphohistiocytosis
Irritable Bowel Syndrome (IBS) - Management Global IBS Symptoms: - Limited trial low FODMAP diet
Irritable Bowel ... Syndrome (IBS) - ... IBS Symptoms: ... intestinal epithelial cells ... #Syndrome #Management
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
Irritable Bowel ... Syndrome (IBS) - ... Diagnosis and Management ... intestinal epithelial cells ... #Irritable #Bowel
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
: Inflammatory eye ... Genital ulcers • Eye ... pathergy test (this is ... #management #signs ... #symptoms #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
limb ischemia, bowel ... WBC >100k, + lab signs ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells ... #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
What Is IRIS ... increase in CD4+ cells ... serositis peritonitis, bowel ... weeks for most OI ... Differential #Diagnosis #Management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Skin: - CLL cells ... smear: Smudge cells ... or basket cells ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Arthralgias • Eye ... purpura: Strong sign ... Multinucleated giant cells ... • Progressive symptoms ... vasculitis • Behcet
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
alterations, and bowel ... • Bilateral signs ... and/or symptoms ... Pleocytosis > 100 cells ... Myelitis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Presentation • Common Signs ... and Symptoms: ... function of NK cells ... and CD8+ T cells ... #Hematology #HemeOnc
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