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Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
Bell's Palsy - Diagnosis ... Imaging (if atypical symptoms ... tears oint + TAPE eye ... within 4m #Bells ... #Treatment #Neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
increase in CD4+ cells ... such as double ... Leishmaniasis Differential ... weeks for most OI ... #Diagnosis #Management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
/ AIDS - Differential ... • IRIS might ... less than 200 cells ... Antimicrobial treatment ... more than 200 cells
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
type (B cell, T cells ... natural killer (NK) cells ... body, but can also ... involvement Differential ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... neoplasms) • Screen also ... glucocorticoid treatment ... Disorders #Algorithm #Differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... pattern of spread, B symptoms ... not as common
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... Lysis of tumor cells ... #diagnosis #management ... #hematology
IDSA Recommendations for Treating Isospora belli Infection in HIV-AIDS
Treating Isospora belli Infection
General Management Considerations:
 • Fluid
Treating Isospora belli ... Treating Isospora belli ... 3–4 weeks) if symptoms ... CD4 count >200 cells ... evidence of active I. belli
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
invades mononuclear cells ... CNS ○ Infected cells ... • Depressive symptoms ... reversible • HAND is also ... dementia #AIDS #Neurology