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differential hematology generalized oncology palpable pruritus purpura rash systemic atlas basics coagulation ddxof dic disseminated intravascular key lesions management mds
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Abnormalities in primary ... or secondary hemostasis ... integrity: - Trauma ... #Algorithm #Causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
and Primary Causes ... == Primary Skin ... • Lymphoma • Leukemia ... #secondary #systemic ... #Algorithm #causes
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
- Diagnostic Algorithm ... vascular integrity (trauma ... or disorders of primary ... or secondary hemostasis ... #Dermatology #Rash
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... • Primary Myelofibrosis ... Post-op surgery • Trauma ... #Algorithm #Causes ... #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Diagnosis Algorithm ... • Lymphoma • Leukemia ... #Algorithm #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Significant ↓ PLT: Petechiae ... + distinctive primary ... bone marrow and secondary ... CLL -> Invade Skin ... #Diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... /Quantity: • Primary ... : ITP • Secondary ... Solar purpura - Trauma
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... associated with secondary ... : Petechiae are ... nettle sting #Diagnosis ... #Dermatology #Skin
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Recent history of trauma ... promyelocytic leukemia ... Manifestations of DIC: • Petechiae ... Treatment: • Treat primary ... #Coagulation #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... by bleeding (petechiae ... DDX: Rule Out Secondary ... • Hairy Cell Leukemia ... Myelodysplastic #Syndromes #diagnosis
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