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hematology differential causes oncology thrombocytosis activation chronic cll hemolytic leukemia lymphocytic macrophage management mas mds microcytic myelodysplasia myelodysplastic petechiae petechial
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... #Anemia #differential ... #diagnosis #algorithm ... #hematology #workup
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... Algorithm by Dr. ... #Algorithm #Diagnosis ... #Workup #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... Post-op surgery • Trauma ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... Schistocytes, thrombocytopenia ... #Algorithm #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... hemolysis, deficiency anemia ... infarction, Severe trauma ... #Algorithm #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... • Neutropenia, anemia ... , thrombocytopenia ... #workup #oncology ... #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Algorithm Pinpoint ... hemostasis: - Thrombocytopenia ... integrity: - Trauma ... deficiency Work ... #dermatology #physicalexam
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... platelet count (thrombocytopenia ... common cytopenia: Macrocytic ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... with leukopenia, anemia ... , and thrombocytopenia ... Activation #Syndrome #Diagnosis ... #Management #Hematology
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