17 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Differential Diaqnoses ... Complications: MAS ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... • Systemic lupus ... SJIA], systemic lupus ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Evolution: Chronic ... disease Dr. ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... rheumatoid arthritis, adult-onset ... : • Chronic B-cell ... Erythematosus #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... cells can indicate disease ... workup #oncology #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... • Evolution: Chronic ... disease Dr. ... #diagnosis #management
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
to Joint Pain - Diagnostic ... ), RA, crystal disease ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology #
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
common leukemia in adults ... immunophenotype Clinical ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Autoimmunity • Chronic ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... Noninflammatory • Trauma ... arthritis • Adult ... #Differential #Diagnosis ... #MSK #rheumatology