12 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... • HLH Labs: ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... also observed in adults ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... diseases: SLE+++, Adult-onset ... Unknown cause Treatment ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... to find in an adult ... (often termed MAS-HLH ... Clinical Presentation ... #Management #Hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Complications: MAS ... #management #treatment ... #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
common leukemia in adults ... immunophenotype Clinical ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Epidemiology: • Young adults ... association • M > F Clinical ... (Clinical Dx). ... Arthritis, AS Treatment ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
history • Young adults ... Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management