11 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Complications: MAS ... hepatitis • Pulmonary ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... fever syndromes Clinical ... Fever is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... also observed in adults ... #management #treatment ... #hematology
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... Summary Clinical ... osteomyelitis, trauma ... necrosis, Lyme disease ... #Management #Summary
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Orange or Hep C Clinical ... cells can indicate disease ... #workup #oncology ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... to find in an adult ... ▪ Autoimmune diseases ... (often termed MAS-HLH ... #Management #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Leukemia (CLL) - Summary ... common leukemia in adults ... immunophenotype Clinical ... #hematology #hemeonc ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
history • Young adults ... Hodgkin Lymphoma - Clinical ... number of sites of disease ... classification #hematology ... #oncology #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Epidemiology: • Young adults ... common in Asia • HLA-B51 ... association • M > F Clinical ... Behcet syndrome (Clinical ... #management #signs