26 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Activation Syndrome (MAS ... arthritis (sJIA) • Adult-onset ... manifestation of MAS ... Plasma exchange #MAS ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... also observed in adults ... : HLH signs and ... acute or subacute ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... diseases: SLE+++, Adult-onset ... #management #treatment ... #summary #rheumatology
Acute Respiratory Distress Syndrome – ARDS: Clinical Cheat Sheet

An acute diffuse, inflammatory lung injury, leading to
Syndrome – ARDS: Clinical ... leading to increased pulmonary ... trauma or sepsis ... Syndrome #ARDS #Summary ... #CheatSheet #Diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Summary Epidemiology ... extrapulmonary cases Clinical ... Signs/Symptoms: ... have signs/symptoms ... #Management #Summary
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... (often termed MAS-HLH ... Clinical Presentation ... • Common Signs ... #Management #Hematology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Summary Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... inflammatory plaques (may ... #Management #dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Orange or Hep C Clinical ... Physical Exam/Signs ... ’s lymphoma or acute ... workup #oncology #hematology
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Shock - Diagnosis ... Full Set of Vital Signs ... Tamponade - Pulmonary ... >> Acute PE, Tension ... #Management #Summary