19 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Complications: MAS ... #management #treatment ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... fever syndromes Clinical ... Fever is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
cardiothoracic surgery, trauma ... • Fluid bolus (Adult ... Plan definitive management ... Intraoperative #Checklist ... #Diagnosis #Management
Efforts to standardize the approach to trauma have led to an algorithmic, thoughtless approach to trauma
the approach to trauma ... prioritized as the critical ... diagnostic step ... #Management #Trauma ... BigTrauma #BeforeCT #Checklist
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... Summary Clinical ... osteomyelitis, trauma ... washout • Healthy Adults ... #Management #Summary
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... anti-lL6R, anti-ILI #Adult ... #rheumatology # ... management
Adrenal hematoma/hemorrhage on FAST exam

Adult male with RUQ/side pain after MVC. Transient prehospital hypotension.  Has
on FAST exam Adult ... Diagnosis/differential ... FAST #Positive #trauma ... #clinical #ultrasound
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Antithrombin Ill • Ultrasound ... ) Differential Diagnosis ... Maternal Support - Critical ... Liver #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... diseases: SLE+++, Adult-onset ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... also observed in adults ... Diagnosis via genetic ... #management #treatment ... #hematology