28 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... also observed in adults ... symptoms can mimic ... #management #treatment ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Diagnosis: • ... Lymphocytic #Leukemia #diagnosis ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... diseases: SLE+++, Adult-onset ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... Fever is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Complications: MAS ... #management #treatment ... #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... common leukemia in adults ... immunophenotype Clinical ... #hemeonc #diagnosis ... #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Epidemiology: young adults ... Autoimmune diseases • Clinical ... Differential Diagnosis ... comparison #oncology #diagnosis ... #differential #hematology
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... Summary Clinical ... osteomyelitis, trauma ... washout • Healthy Adults ... #Management #Summary
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
- Differential Diagnosis ... Algorithm Clinical ... ptosis with CN Ill ... • Neurologic ... symptoms suggest
Indications for tPA in Stroke:
 • Clinical diagnosis of ischemic stroke
 • Measurable neurologic deficit
 •
in Stroke: • Clinical ... diagnosis of ischemic ... deficit • Onset of symptoms ... Ischemic stroke, head trauma ... #Stroke #cva #management