9 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Adult form: Less ... • Pernicious anemia ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... Fever is the main clinical ... with leukopenia, anemia ... tests ↑ AST ↑ ALT ... Activation #Syndrome #Diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Rhabdomyolysis: • Trauma ... Dermatomyositis Clinical ... #Differential #Diagnosis ... causes #treatment #nephrology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... the Journal of Clinical ... mL in a 70 kg adult ... deficiencies • Renal ... of renal disease
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Meningococcal), surgery, trauma ... transplantation CLINICAL ... complete paralysis of all ... the underlying pathophysiology ... #management #neurology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis (SRC) Clinical ... microangiopathic hemolytic anemia ... (MAHA) Pathophysiology ... #rheumatology #nephrology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
• In all patients ... to find in an adult ... Clinical Presentation ... - Cytopenias (anemia ... Pathophysiology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... Diagnosis (Clinical ... Normal kidney ultrasound ... evaluation essential in all ... Syndrome #Hepatology #Nephrology
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
fasting/weight loss RENAL ... / Hypovolemia NEUROLOGIC ... lymphocytosis, mild anemia ... Complications #pathophysiology ... #diagnosis #signs