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management treatment causes differential hematology disease hemophagocytic hlh lymphohistiocytosis mas stills acidbase acidosis adultonset adverse algorithm alkalosis aosd arthritis autoimmune
Important Respiratory Distress Pearls #diagnosis #respiratory #distress #NRDS #RDS #TTN #MAS #neonatal #pediatric #adult #respiratory #adverse #effects
Important Respiratory ... Distress Pearls #diagnosis ... #respiratory #distress ... NRDS #RDS #TTN #MAS ... neonatal #pediatric #adult
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... arthritis (sJIA) • Adult-onset ... #Macrophage #Activation ... #Syndrome #Diagnosis ... #Rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... Stills #Disease #diagnosis ... management #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... Auto-amplification loop Diagnosis ... diseases: SLE+++, Adult-onset ... treatment #summary #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... • Leukocytosis Diagnosis ... mL Gf consider MAS ... anti-lL6R, anti-ILI #Adult ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... also observed in adults ... Presentation / Diagnosis ... Diagnosis via genetic ... management #treatment #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... Noninflammatory • Trauma ... arthritis • Adult ... #Differential #Diagnosis ... #MSK #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Recent history of trauma ... dysfunction (19%) • Respiratory ... #Coagulation #diagnosis ... treatment #management #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... rheumatoid arthritis, adult-onset ... Non-autoimmune rheumatologic ... Chronic B-cell activation ... #Rheumatology
Differential Diagnosis of Respiratory Acid-Base Disorders Alkalosis A. Central nervous system stimulation: Pain, Anxiety, psychosis, Fever, Cerebrovascular accident,
Differential Diagnosis ... of Respiratory ... encephalitis, Tumor, Trauma ... Pneumoconiosis, Bronchitis, Adult ... #differential #diagnosis
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