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management rheumatology differential adultonset arthritis endocarditis hematology hemophagocytic hlh lymphohistiocytosis summary accaha activation bronchiectasis chf classes classification congestive francisella fungal
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... : High spiking fever ... : high fever, CRP ... #Disease #AOSD
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... Complications: MAS ... #Disease #diagnosis ... #management #treatment
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... #onset #Stills ... #disease #AOSD #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... Still disease ... erythematosus [SLE], AOSD ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
active ROM +/- fever ... , chills, malaise ... osteomyelitis, trauma ... necrosis, Lyme disease ... Treatment: admission
Tularemia - Diagnosis and Management Summary Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection •
Ulceroglandular: Fever ... More common in adults ... : • Severe Disease ... #management #treatment ... #infectiousdiseases
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... • Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... Noninflammatory • Trauma ... • Rheumatic fever ... arthritis • Adult ... onset Still's
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Generalized: • Chills ... night sweats, fever ... Paradoxical emboli via ASD ... Persistent bacteremia/fevers ... #management #cardiology
In order to better classify heart failure, the American College of Cardiology Foundation and the American
symptoms, can still ... With treatment, ... structural heart disease ... in patients who never ... #Diagnosis #Cardiology
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