18 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... Complications: MAS ... #Disease #diagnosis ... #management #treatment
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... : High spiking fever ... #AdultOnset #Stills ... #Disease #AOSD
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #onset #Stills
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... • Clinical: fever ... : SLE+++, Adult-onset ... Still disease,
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... arthritis (sJIA) • Adult-onset ... Still disease ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
active ROM +/- fever ... , chills, malaise ... osteomyelitis, trauma ... necrosis, Lyme disease ... Treatment: admission
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
Ulceroglandular: Fever ... More common in adults ... : • Severe Disease ... #management #treatment ... #infectiousdiseases
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
disease caused ... , malaise, chills ... Nodular → Mular DIAGNOSIS ... TREATMENT: ​• Acute ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... age, however the disease ... also observed in adults ... following: • Fever ... • Bicytopenia Treatment
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... mild (malaise, fever ... , reactivation in ... Standard regimen: Adult ... Regimens: • Adult