21 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... disorders • Celiac disease ... Post-op surgery • Trauma ... effect following treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... #diagnosis #management ... #treatment #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... suspicion of severe disease ... - Sickle cell disease ... #Child #Peds #Pediatrics ... #Diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
rarely occurs in adults ... , Cough • +/-Nausea ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi ... #management #treatment
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
osteomyelitis, trauma ... necrosis, Lyme disease ... Treatment: admission ... 90% sensitive in pediatrics ... but NOT adults
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
, Trauma, Surgery ... uropathy, Metabolic causes ... Treatment is aimed ... Classification #Types #Nephrology ... #Diagnosis #Differential
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... Treatment: • ... #management #treatment
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Causes of Peripheral ... often in older adults ... Méniére's disease ... #differential #diagnosis ... #neurology