7 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Fever, Arthralgia/arthritis ... Complications: MAS ... #Disease #diagnosis ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... (sJIA) • Adult-onset ... Still disease ... manifestation of MAS ... Plasma exchange #MAS
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
ROM +/- fever, chills ... osteomyelitis, trauma ... necrosis, Lyme disease ... diagnosis Treatment ... 90% sensitive in pediatrics
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #onset #Stills
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... Noninflammatory • Trauma ... • Adult onset ... Still's • Ankylosing ... #Differential #Diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... , adult-onset Still ... erythematosus (NPSLE): • May ... Chronic B-cell activation ... Erythematosus #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
by uncontrolled activation ... to find in an adult ... - Common in: Adults ... ▪ Autoimmune diseases ... (often termed MAS-HLH