11 results
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
vascular integrity (trauma ... affected (commonly renal ... and pulmonary ... #Diagnosis #Dermatology ... #Rash #Petechiae
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... arthritis, Skin rash ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(MAS) Classified ... manifestation of MAS ... Petechial or purpuric rash ... Plasma exchange #MAS ... #Diagnosis #Management
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
usually to TEN in adults ... erythematous rash ... Nikolsky sign may ... #Diagnosis #Dermatology ... #Erythematous #Rash
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... anti-lL6R, anti-ILI #Adult ... #rheumatology # ... management
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
Toxins (CCB, BB, BRASH ... syndrome etc), ... Cardiac Tamponade, Pulmonary ... ), Renal Losses( ... Undifferentiated #Shock #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... rheumatoid arthritis, adult-onset ... Malignancy (e.g. hematologic ... APLA/LAC: • Renal ... Erythematosus #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... vein: Budd-chiari syndrome ... , CMV, VZV • Trauma ... #algorithm #hepatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... and renal abnormalities ... Vasculitis Differential Diagnosis ... , mucositis • Rash ... #Rheumatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... - CRS: fever, rash ... , hypotension, renal ... failure, pulmonary ... Oncology #HemeOnc #Diagnosis