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management hematology hemophagocytic hlh infectiousdiseases lymphohistiocytosis activation adultonset arteritis cap community disease fusarium gca giantcell hemeonc infections macrophage mas pneumonia
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
the secondary or acquired ... arthritis (sJIA) • Adult-onset ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Purtilo (XLP) Acquired ... diseases: SLE+++, Adult-onset ... #summary #rheumatology
Community Acquired Pneumonia (CAP) - Diagnosis and Management Pneumonia Signs/Symptoms: • Confusion/disorientation (LR + 1.9) • Cough
Community Acquired ... Pneumonia (CAP) - Diagnosis ... be initiated in adults ... with clinically ... #Pulmonary #Community
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... Diagnosis = clinical ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology
Toxocariasis Pathogen: Toxocara - worldwide distributed helminth Transmission: • Dogs and cats are the major source
• Humans acquire ... Adult worms develop ... larva migrans Diagnosis ... • History + clinical ... #microbiology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
to find in an adult ... • Secondary (Acquired ... - Common in: Adults ... (often termed MAS-HLH ... Clinical Presentation
Fusarium Infections Acquired through: 1. Inhalation of airborne conidia > germinates > blood > disseminated 2. Trauma (implantation with
Fusarium Infections Acquired ... Trauma (implantation ... incubation 4 major clinical ... Refractory FUO, Sino-pulmonary ... disease: • Optimal treatment
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