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rheumatology disease hematology hemophagocytic hlh infectiousdiseases lymphohistiocytosis stills syndrome adultonset airway anatomy anesthesia anesthesiology aosd barre cap cardiac checklist community
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... the secondary or acquired ... manifestation of MAS ... Plasma exchange #MAS ... #Syndrome #Diagnosis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... Purtilo (XLP) Acquired ... diseases: SLE+++, Adult-onset ... #management #treatment
Leptospirosis Pathogen: Leptospira (interrogans, kirschneri, noguchii) Risk Factors: • Occupational exposure - Farmers, ranchers, trappers, veterinarians • Recreational
failure • Severe pulmonary ... manifestations • MAT ... Leptospirosis #Leptospira #microbiology ... #diagnosis #treatment ... #management
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #management
Community Acquired Pneumonia (CAP) - Diagnosis and Management Pneumonia Signs/Symptoms: • Confusion/disorientation (LR + 1.9) • Cough
Pneumonia (CAP) - Diagnosis ... and Management ... be initiated in adults ... #Management #treatment ... #Pulmonary #Community
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... to find in an adult ... • Secondary (Acquired ... - Common in: Adults ... (often termed MAS-HLH
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
cardiothoracic surgery, trauma ... thoracotomy is a better treatment ... • Fluid bolus (Adult ... a small volume may ... #Management #Workup
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Meningococcal), surgery, trauma ... bulbar muscles DIAGNOSIS ... and cauda equina TREATMENT ... ventilation is required ... #management #neurology
Toxocariasis Pathogen: Toxocara - worldwide distributed helminth Transmission: • Dogs and cats are the major source
• Humans acquire ... the infection as ... Adult worms develop ... #management #infectiousdiseases ... #treatment #microbiology
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