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management disease infectiousdiseases stills activation adultonset aosd arteritis bacteria cap community fusarium gca giantcell hematology hemophagocytic hlh infections lymphohistiocytosis macrophage
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Rhodococcus - Microbiology Overview Microbiology: • Facultative, intracellular, nonmotile, non-spore-forming • Aerobic acid-fast gram-positive coccobacilli • Produces
Rhodococcus - Microbiology ... inoculation due to trauma ... Diagnosis Treatment ... #diagnosis #treatment ... #pulmonary #Bacteria
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
the secondary or acquired ... arthritis (sJIA) • Adult-onset ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Purtilo (XLP) Acquired ... diseases: SLE+++, Adult-onset ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Community Acquired Pneumonia (CAP) - Diagnosis and Management Pneumonia Signs/Symptoms: • Confusion/disorientation (LR + 1.9) • Cough
Community Acquired ... Pneumonia (CAP) - Diagnosis ... be initiated in adults ... #Management #treatment ... #Pulmonary #Community
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology ... w/in 24 hours) required
Toxocariasis Pathogen: Toxocara - worldwide distributed helminth Transmission: • Dogs and cats are the major source
• Humans acquire ... Adult worms develop ... larva migrans Diagnosis ... are not helpful Treatment ... #microbiology
Fusarium Infections Acquired through: 1. Inhalation of airborne conidia > germinates > blood > disseminated 2. Trauma (implantation with
Fusarium Infections Acquired ... Trauma (implantation ... Refractory FUO, Sino-pulmonary ... disease: • Optimal treatment ... infectiousdiseases #diagnosis
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