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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic Lupus ... Lupusreference #TMAs ... Microangiopathies #Systemic #Lupus ... Erythematosus #SLE #hematology ... differential #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... Clinical Presentation ... SJIA], systemic lupus ... #Diagnosis #Management ... #Hematology #Rheumatology
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... of Systemic Lupus ... ) #Systemic #Lupus ... Signs #Symptoms #Rheumatology ... #Diagnosis
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Goldberg, M.D. - UCSD ... Catalog of Clinical ... Images #Clinical ... #Dermatology #SkinRash ... #DRESS #Syndrome
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Goldberg, M.D. - UCSD ... Catalog of Clinical ... Images #Clinical ... #Dermatology #SkinRash ... #DRESS #Syndrome
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... suspect underlying hematologic ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... , Drug-induced Lupus ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Erythematosus Clinical ... pericarditis • Hematologic ... Erythematosus #diagnosis ... #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... Antiphospholipid Antibody Syndrome ... glycoprotein I (ß2GP), Lupus ... LAC) • Sjogren Syndrome ... #diagnosis #associations
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
- Differential Diagnosis ... Wiskott-Aldrich syndrome ... Diseases: • Systemic lupus ... #Differential #Diagnosis ... #Hematology