37 results
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Lupusreference #TMAs ... Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... fraction < 20% Differential ... Complications: MAS ... diagnosis #management #treatment ... #rheumatology
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Proposed Treatment ... Algorithm for MAS ... / HLH #MAS # ... Lymphohistiocytosis #Management #Treatment ... #Algorithm #Hematology
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Still's disease ... Hyperferritinemia #Algorithm #Differential ... #Diagnosis #Hematology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... synovitis (40%) Treatment ... #AdultOnset #Stills ... Disease #AOSD #rheumatology ... diagnosis #management #treatment
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
Inflammatory Arthritis - Differential ... , Sarcoidosis, Still's ... #arthritides #Differential ... #Diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Activation Syndrome (MAS ... • Adult-onset Still ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Initial triage of the neutropenic adult - Algorithm for the evaluation and treatment of adult patients
evaluation and treatment ... workup #diagnosis #hematology ... #indications #differential
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... AOSD #diagnosis #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Thrombocytosis #Platelets #Differential