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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Thrombotic Microangiopathies ... Lupusreference #TMAs ... #Thrombotic #Microangiopathies ... #rheumatology # ... differential #diagnosis
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... /HUS indicates thrombotic ... thrombocytopenic ... , Hematology 2012 ... , p 193 #Diagnosis
Thrombotic Thrombocytopenic Purpura (TTP) vs Disseminated Intravascular Coagulation (DIC)
#Diagnosis #TTP #DIC #Comparison #Table #Laboratory #Findings #RebelEM
Thrombotic Thrombocytopenic ... Coagulation (DIC) #Diagnosis ... Findings #RebelEM #Thrombocytopenia
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... testing for TTP #Thrombotic ... Microangiopathy #thrombocytopenic ... #Comparison #Diagnosis ... #Table #Hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... - TMAs 1. ... triad of MAHA + thrombocytopenia ... @AnnKumfer #Thrombotic ... #hematology #diagnosis
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... The diagnosis of ... are initially diagnosed ... #Diagnosis #Hematology ... #Thrombocytopenia
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic ... Purpura (TTP) Diagnosis ... soon as TTP is diagnosed ... #Thrombocytopenic ... management #treatment #rheumatology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
- Primary Thrombotic ... - Differential Diagnosis ... Thrombocytopenic ... Microangiopathy #TMA #hematology ... #differential #diagnosis
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Idiopathic Thrombocytopenic ... ITP #Idiopathic #Thrombocytopenic ... #Purpura #Thrombocytopenia ... #Diagnosis #Overview ... #Hematology
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Heparin-Induced Thrombocytopenia ... score: - Thrombocytopenia ... - Thrombosis ... #HIT #hematology ... #diagnosis #4Ts