8 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Complications: MAS ... Prunelle Getten #AdultOnset ... #Stills #Disease ... #diagnosis #management ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... • Adult-onset Still ... manifestation of MAS ... Treatment: • Corticosteroids ... Plasma exchange #MAS
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #management
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS
Preventing Clinical Disease
Indication:  Individuals
duration same as ... for treatment of ... treated patients are still ... Note: Treatment ... #management #opportunistic
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Fever Hematologic disease ... fever, malaise, chills ... jaundice ​• Neuro: AMS ... TREATMENT: ​• Acute ... Fever #diagnosis #management
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
P. h. humanus sticks ... LBRF was epidemic ... The table below ... initiation of treatment ... Infectious Diseases
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... by uncontrolled activation ... ▪ Autoimmune diseases ... (often termed MAS-HLH ... Treatment Approach
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
But can still have ... had more severe disease ... Dermatomyositis: • ILD was ... positive patients Treatment ... Dermatomyositis #diagnosis #management