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diagnosis rheumatology treatment abscess adult adultonset antinxp2 antinxp2dm aosd bacilliformis bartonella bloodsmear borrelia clinical dermatology dermatomyositis differential fever hematology hemophagocytic
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Complications: MAS ... #AdultOnset #Stills ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... • Adult-onset Still ... manifestation of MAS ... Plasma exchange #MAS ... Syndrome #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... +, Adult-onset Still ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... mL Gf consider MAS ... #Adult #onset #Stills ... #rheumatology #management
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Diagnosis and Management ... • Most common cause ... 38 degrees • Chills ... Lung Abscess Management ... #differential #causes
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Fever Hematologic disease ... caused by Bartonella ... fever, malaise, chills ... coinfection, toxo reactivation ... Fever #diagnosis #management
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
BP stable, HR 115 ... P. h. humanus sticks ... LBRF was epidemic ... The table below ... Infectious Diseases
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
But can still have ... Muscle atrophy may cause ... had more severe disease ... Dermatomyositis: • ILD was ... Dermatomyositis #diagnosis #management
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