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differential algorithm causes management oncology workup aplastic disorders enzymes leukemia lfts liver macrocytic microangiopathy microcytic neutropenia platelet platelets thrombocytopenia thrombocytosis
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Normal range 11.5% ... in bone marrow (BM ... under 2%, then BM ... #Workup #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... Initial labs: CBC, BMP ... hemosiderin • PT/aPTT normal ... Management #Algorithm #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... workup, including BM ... hemolysis, deficiency anemia ... Acute bacterial and ... #Algorithm #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
evaluation of the pattern ... Areas of diagnostic ... aminotransferase; BMI ... #Algorithm #Hepatology ... #Differential #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... function test, ANA ... changes), high MCV anemia ... When do you do a BM ... Causes #Workup #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... syndrome (MDS) (normal ... a normal or increased ... #oncology #hematology ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... replacing the BM ... Megaloblastic anemia-rare ... replacing the BM-common ... #causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
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